Making believers out of the skeptical night after night, Saxsquatch brings the myth, magic, and music as only a legendary cryptid can.
Being part rave, part jazz fusion fest, part elevator music tones, and part Bigfoot cosplay, the Saxsquatch show at The Radio Room in Greenville, SC was unlike anything I’ve seen before, yet perfectly recognizable for what it was: a good time on a Saturday night.
Saxsquatch, who goes by his alter-ego name of Dean Mitchell when not on stage, is a product of Chapel Hill, NC. Who knew Bigfoot was a local boy? Graduating from playing saxophone with the Marcus King Band, Saxsquatch broke out on his own when his cover of Daft Punk’s “One More Time” went viral in 2019. Millions of viewers became believers and Saxsquatch became a phenomenon. Tours ensued and other mythical beings came out to support him alongside his new believers. Most importantly though, as Saxsquatch himself states repeatedly during his live show, he believes in YOU as much as you believe in him and therein lies the true magic that Mitchell conjures as Saxsquatch.
The one man show that is Saxsquatch is something to behold, and it’s not just the 7 foot bigfoot wailing on a saxophone between the trees, fog machine excretions, and spaced out laser lights emanating from the stage. Saxsquatch has the natural ability to draw out fellow squatches, spacemen, aliens (greens and greys), and humans ranging from grade school age to near retirement home age. Uniting such a diverse crowd of humans and beings under disco ball cast stars that shine through a haze of sax, dub, and beats is all in a night’s stomp for this cryptid.
Saxsquatch isn’t all X-Files kitsch though. Mitchell is quite the serious musician. Aside from his serious sax skills, he is also a talented electronica composer and performer. His postmodern mix of sultry, swinging, and bebopping saxophone riffs and electronic sampling, rhythms, and atmospherics is actually something unique in an era of cookie cutter pop songs and unoriginal studio manufactured rock. Mitchell indulges in some covers, most notably “Wayward Son” by Kansas and the “Mos Eisley Cantina Song” composed by John Williams, but also performs a set of original compositions such as “Hide and Seek Pt. 2” and “Madness.”
The most striking thing about a Saxsquatch show though is the vibe. Repeatedly expressing verbal displays of love for his believers, fellow cryptids, and fans of all ages, Saxsquatch simply radiates good feeling, joy, community, and hope. “Remember, I believe in YOU!” isn’t just a mantra for Saxsquatch to repeat to get the crowd going. It’s strangely transcendent. Never in my wildest dreams did I think a musician in a bigfoot costume who played the saxophone over electronic beats would be so inspiring, but that’s kinda the point of belief in the fantastic isn’t it? I no longer want to believe. Thanks to saxsquatch, I do believe.

















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January 30, 2026 at 6:32 pm
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Diflucan
January 30, 2026 at 6:31 pm
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Diflucan loading doses are used to achieve therapeutic levels rapidly in serious infections.
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January 30, 2026 at 6:28 pm
Activity against dermatophytes underpins its use in extensive tinea infections.
Fluconazole
January 30, 2026 at 6:28 pm
Diflucan is often compared to echinocandins in candidemia treatment guidelines.
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Fungicidal activity is observed only at very high concentrations against some species.
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Its generic availability has dramatically reduced treatment costs globally.
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January 30, 2026 at 6:19 pm
Its high selectivity for fungal enzymes over human ones is key to its relatively low toxicity.
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January 30, 2026 at 6:10 pm
Diflucan is not recommended for treatment of fungal endocarditis.
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January 30, 2026 at 6:07 pm
Development of the IV formulation expanded use to critically ill and unable-to-swallow patients.
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Requires caution with other QTc-prolonging agents to avoid torsades de pointes.
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Diflucan may be used for step-down therapy after initial echinocandin treatment for candidemia.
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QTc prolongation is a boxed warning for Diflucan, especially at high doses or with other agents.
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January 30, 2026 at 6:00 pm
Diflucan is often the reference agent in comparative antifungal clinical trials.
Fluconazole
January 30, 2026 at 6:00 pm
Not effective against Histoplasma in the central nervous system due to poor penetration (unlike itraconazole).
Fluconazole
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Diflucan may deplete coenzyme Q10 with long-term use, a theoretical concern.
Diflucan
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Its legacy is its role in making systemic antifungal therapy outpatient-friendly and accessible.
Fluconazole
January 30, 2026 at 5:58 pm
Diflucan is ineffective against Candida auris, a major multidrug-resistant pathogen.
Diflucan
January 30, 2026 at 5:58 pm
A cornerstone of antifungal therapy in resource-limited settings due to cost and availability.
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Diflucan (Fluconazole)
January 30, 2026 at 5:55 pm
Diflucan is not active against Trichosporon species.
Diflucan
January 30, 2026 at 5:52 pm
Diflucan is often used for prophylaxis in stem cell transplant recipients.
Fluconazole
January 30, 2026 at 5:52 pm
Not reliably effective in fungal endocarditis, where fungicidal therapy is preferred.
Fluconazole (Diflucan)
January 30, 2026 at 5:52 pm
Diflucan is a valuable tool for treating susceptible Candida urinary tract infections.
Diflucan
January 30, 2026 at 5:51 pm
Diflucan resistance can emerge during long-term suppressive therapy.
Diflucan (Fluconazole)
January 30, 2026 at 5:50 pm
Multiple drug interactions stem from its inhibition of human CYP2C9 and CYP3A4.
Diflucan
January 30, 2026 at 5:49 pm
Concurrent use with statins metabolized by CYP3A4 increases risk of myopathy/rhabdomyolysis.
Diflucan (Fluconazole)
January 30, 2026 at 5:47 pm
Diflucan exhibits fungistatic, not fungicidal, activity against most susceptible yeasts.
Diflucan
January 30, 2026 at 5:43 pm
Its use in veterinary medicine parallels many human applications.
Diflucan
January 30, 2026 at 5:42 pm
Diflucan is available as a branded product and multiple generic equivalents.
Diflucan
January 30, 2026 at 5:40 pm
The “trailing effect” in Diflucan susceptibility testing can complicate interpretation.
Diflucan (Fluconazole)
January 30, 2026 at 5:40 pm
Diflucan achieves high concentrations in vaginal tissue, explaining its efficacy.
Diflucan
January 30, 2026 at 5:39 pm
Fungicidal activity is observed only at very high concentrations against some species.
Diflucan (Fluconazole)
January 30, 2026 at 5:36 pm
Diflucan’s chemical structure gives it high water solubility.
Fluconazole
January 30, 2026 at 5:36 pm
Concomitant Diflucan and warfarin requires intense INR monitoring due to increased bleeding risk.
Fluconazole (Diflucan)
January 30, 2026 at 5:36 pm
Diflucan lacks activity against Histoplasma in the CNS, unlike itraconazole.
Diflucan
January 30, 2026 at 5:35 pm
Breakthrough infections during prophylaxis are a significant clinical red flag.
Diflucan (Fluconazole)
January 30, 2026 at 5:33 pm
Excellent CSF penetration makes it a mainstay for cryptococcal meningitis suppression.
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Diflucan (Fluconazole)
January 30, 2026 at 5:31 pm
A paradigm for how a single molecule can transform the management of a wide range of fungal diseases.
Diflucan
January 30, 2026 at 5:26 pm
Its use in veterinary medicine parallels many human applications.
Diflucan
January 30, 2026 at 5:23 pm
Plays a role in step-down therapy after initial echinocandin treatment for candidemia.
Diflucan
January 30, 2026 at 5:22 pm
Teratogenicity concerns (Category D) limit its use in pregnancy, especially first trimester.